Web29 jun. 2024 · The role of HSP47 in intestinal fibrosis has been investigated by Kitamura et al., who found that transcription of SERPINH1, which encodes HSP47, was elevated in … Web9 feb. 2001 · A preliminary experiment showed that down-regulation of HSP47 caused the reduction in the progression of fibrosis by down-regulating the accumulation of collagens in the tissues, which suggests a novel strategy for the therapy of fibrotic diseases including liver cirrhosis. 14 PDF
HSP47: a potential target for fibrotic diseases and implications for ...
WebHeat shock protein 47 (HSP47), a collagen-specific molecular chaperone, is essential for the biosynthesis and secretion of collagen and is expressed in the fibrotic peritoneum. In the present study, Web24 sep. 2024 · Overall, we demonstrated that HSP47 is a potential therapeutic target for pulmonary fibrosis. The small molecule HSP47 inhibitor may mediate antifibrotic effects … say something james live
(PDF) Anti-HSP47 siRNA Lipid Nanoparticle ND-L02-s0201 …
Web29 mrt. 2024 · IL-17A-induced HSP47 expression is involved in collagen I expression in intestinal subepithelial myofibroblasts, which might contribute to intestinal fibrosis in … WebProfibrotic behavior of fibroblasts derived from patients that develop posttraumatic shoulder stiffness - PMC Back to Top Skip to main content An official website of the United States government Here's how you know The .gov means it’s official. Federal government websites often end in .gov or .mil. Web4 apr. 2005 · HSP47 is a heat shock protein that functions as a specific chaperone for procollagen molecules as they transit through the endoplasmic reticulum. 1 Although the … say something in morse code