WebMar 20, 2024 · The pathogenesis of ricin toxicity following inhalation has been investigated in many animal models, including the non-human primate (predominantly the rhesus macaque), pig, rabbit and rodent. The toxicity and associated pathology described in animal models are broadly similar, but variation appears to exist. This paper reviews the … WebMay 1, 2024 · National Center for Biotechnology Information
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WebMay 10, 2024 · Exposure duration (ED) is the amount of time that an individual or population is exposed to the contaminant being evaluated and is typically provided in years. Averaging time (AT) is the amount of time over which exposure is averaged and is equal to ED for assessing non-cancer risks. For chronic assessments (e.g., cancer), potential … WebChronic Toxicity (or Exposure) Animal. In chronic toxicity studies, liver and kidneys were the principal target organs. Exposure to 1,2-dichloroethane by gavage for 78 weeks induced … early breakfast fort william
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